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Genetic and epigenetic editing of tumour cells and the microenvironment to block metastasis
Siberian State Medical University
Clinical trials of medicines
Validation of medication
Diagnostic test systems
3D humanised models for pre-clinical work
Integrated education programmes and research
Raising domestic and international funding
Commercialization
Development of the Patient School in the Russian Federation
Project partners
Project Relevance
Genotherapeutic products and technologies
Infrastructure for genetic engineering
Masters and PhD students in genetic and biotechnology
Cancer patient schools
International Conference
«Genetic Technologies
in Translational Biomedicine»
Tomsk city, 6-8 September 2023
erid: 2VtzquYUVgb
Full info
Main ideas of the project
Blocking the transition of micrometastases to macrometastases at the level of the dedifferentiation process
Epigenetic reprogramming of macrophages
Antimetastatic stimulation of local and systemic immunity
Expected key results
Genotherapeutic medicines
Genetically modified microorganisms to stimulate systemic anti-metastatic immunity
Genetically engineered microRNA constructs to block the metastatic potential of cancer cells
Gene technologies
Epigenetic editing of immunity
Test system for drugs blocking the transition from micrometastases to macrometastases
Genotechnology for the prognosis of the course of tumours in 7 localisations
Infrastructure for genetic engineering
Spatial profiling of the genome and transcriptome in situ using Nanostring technology
3D bioprinting centre for preclinical research